STUDIES ON FREE ERYTHROCYTE PROTOPORPHYRIN, PLASMA IRON AND PLASMA COPPER IN NORMAL AND ANEMIC SUBJECTS

Studies on free erythrocyte protoporphyrin, plasma iron and plasma copper in normal and anemic subjects.

T HE VARIOUS anemias have been studied and classified clinically, morphologically, therapeutically and to a less extent etiologically, but comparatively few chemical studies have been made. Investigation of the chemical changes accompanying the various types of anemia offers a new approach to their study and gives rise to the hope that as the specific defects are elucidated their correction wil...

Studies on free erythrocyte protoporphyrin, plasma copper, and plasma iron in normal and in pyridoxine-deficient swine.

Previous communications from this laboratory (l-7) have demonstrated that swine maintained on a highly purified diet deficient in pyridoxine develop a severe anemia which is characterized by microcytosis, slight hypochromia, and an increase in polychromatophilia, reticulocytes, and nucleated red cells in the blood. There is a marked hyperferremia, normoblastic bone marrow hyperplasia, myelin de...

Studies on Free Erythrocyte Protoporphyrin, Serum Iron, Serum Iron-binding Capacity and Plasma Copper during Normal Pregnancy.

Indicators of the iron status of populations: free erythrocyte protoporphyrin and zinc protoporphyrin; serum and plasma iron, total iron binding capacity and transferrin saturation; and serum transferrin receptor

Red Cell and Plasma Radioactive Copper in Normal and Anemic Dogs

Following ingestion of radioactive copper by the dog, the metal appears quickly in the plasma, the concentration reaching its peak in from 2 to 5 hours, after which it falls abruptly. Demonstrable amounts are still present after 2 days. The radioactive copper likewise appears rapidly in the circulating red blood cells, and there is a slow but gradual increase in its concentration over a 2 day p...